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Uses
To clean and inactivate most anticancer drugs on chemotherapy work surfaces.
Description and Purpose
Surface Safe is made up of two packets and is packaged in boxes containing 15 double packets (15 pairs/box). Each pair of packets provides enough solution to treat about a 2-square-foot area.
Packet 1
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Contains a 5.5 x 10 in. towelette in a 2% (w/w) sodium hypochlorite Na(OCl2) soap solution
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Has a high level of oxidizing activity which inactivates potent anticancer agents
Packet 2
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Contains a 5.5 x 10 in. towelette in 1% (w/w) sodium thiosulfate with 0.9% (w/w) benzyl alcohol
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Rapidly inactivates the hypochlorite in the first packet to reduce toxic potential and long-term damage to insert surfaces
[Note: This reaction is slightly exothermic (produces heat)]
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Instructions
Surface Safe® packets are to be used in numerical order. Latex or rubber gloves must be worn when using this product.
1) Carefully open packet 1 and apply the pre-moistened towelette vigorously to the area to be treated.
2) Allow the treated area to set for at least 30 seconds.
3) Open packet 2 and apply the pre-moistened towelette to the area previously treated with packet 1.
4) If needed, the area may now be cleaned with an alcohol swab or simple soap solution (not provided) to remove any inactivated residue.
5) Dispose of used towelettes in a chemotherapy waste container.
Drugs Surface Safe Inactivates
A number of active drugs have been found to be inactivated by directly applying Surface Safe Packets. Any anticancer agent which can undergo oxidative or alkaline degradation can be inactivated, including the following:
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Anthracyclines, such as doxorubicin, daunorubicin and epirubicin
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Anthracenes, such as mitoxantrone and bisantrene
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Alkylating agents, such as mitomycin, melphalan, cyclophosphamide, ifosphamide, thio-TEPA, dacarbazine, carmustine, cisplatin and carboplatin
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Antimetabolites, such as fluorouracil, cytarabine, and mercaptopurine
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Biologicals, such as alpha-interferon, interleukin-2, tumor necrosis factor,
G-CSF and GM-CSF
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Miscellaneous compounds, such as paclitaxel, docetaxel, vinblastine, vincristine, vindesine, vinorelbine, topotecan, irinotecan, etoposide, teniposide,amsacrine (mAMSA), dactinomycin, bleomycin, L-asparaginase
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